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CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice

Sialic acid-binding immunoglobulin-like lectins (Siglecs) are expressed in various immune cells and most of them carry signaling functions. High-affinity synthetic sialoside ligands have been developed for various Siglecs. Therapeutic potentials of the nanoparticles and compounds that contain multip...

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Detalles Bibliográficos
Autores principales: Matsubara, Naoko, Imamura, Akihiro, Yonemizu, Tatsuya, Akatsu, Chizuru, Yang, Hongrui, Ueki, Akiharu, Watanabe, Natsuki, Abdu-Allah, Hajjaj, Numoto, Nobutaka, Takematsu, Hiromu, Kitazume, Shinobu, Tedder, Thomas F., Marth, Jamey D., Ito, Nobutoshi, Ando, Hiromune, Ishida, Hideharu, Kiso, Makoto, Tsubata, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917077/
https://www.ncbi.nlm.nih.gov/pubmed/29725338
http://dx.doi.org/10.3389/fimmu.2018.00820