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Developmental Defects in Trisomy 21 and Mouse Models

Aneuploidies have diverse phenotypic consequences, ranging from mental retardation and developmental abnormalities to susceptibility to common phenotypes and various neoplasms. This review focuses on the developmental defects of murine models of a prototype human aneuploidy: trisomy 21 (Down syndrom...

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Detalles Bibliográficos
Autores principales: Delabar, Jean Maurice, Aflalo-Rattenbac, Revital, Créau, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917200/
https://www.ncbi.nlm.nih.gov/pubmed/17205199
http://dx.doi.org/10.1100/tsw.2006.322