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Using Protein Homology Models for Structure-Based Studies: Approaches to Model Refinement
Homology modeling is a computational methodology to assign a 3-D structure to a target protein when experimental data are not available. The methodology uses another protein with a known structure that shares some sequence identity with the target as a template. The crudest approach is to thread the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917253/ https://www.ncbi.nlm.nih.gov/pubmed/17160340 http://dx.doi.org/10.1100/tsw.2006.250 |