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Platelets as Modifiers of Clinical Phenotype in Hemophilia

Platelets occupy a central role in the maintenance of hemostasis by adhering to sites of vascular injury and facilitating thrombin generation, which leads to the formation of a fibrin clot. Patients with hemophilia exhibit defective thrombin generation secondary to reduced plasma factor concentratio...

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Detalles Bibliográficos
Autor principal: Yee, Donald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917339/
https://www.ncbi.nlm.nih.gov/pubmed/16832569
http://dx.doi.org/10.1100/tsw.2006.133