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Platelets as Modifiers of Clinical Phenotype in Hemophilia
Platelets occupy a central role in the maintenance of hemostasis by adhering to sites of vascular injury and facilitating thrombin generation, which leads to the formation of a fibrin clot. Patients with hemophilia exhibit defective thrombin generation secondary to reduced plasma factor concentratio...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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TheScientificWorldJOURNAL
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917339/ https://www.ncbi.nlm.nih.gov/pubmed/16832569 http://dx.doi.org/10.1100/tsw.2006.133 |