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Activated K‐ras in Tumorigenic and Non‐tumorigenic Cell Variants from a Rat Colon Adenocarcinoma, Induced by Dimethylhydrazine
Using NIH3T3 cell transfection assay, activated c‐K‐ras was detected in two cell lines, TRb and TSb, obtained from a single colon adenocarcinoma induced in a rat by 1,2‐dimethylhydrazine. TRb cells give rise to progressive and metastatic tumors in the syngeneic rats, whereas TSb cells only induce re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917453/ https://www.ncbi.nlm.nih.gov/pubmed/3130359 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01583.x |