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Activated K‐ras in Tumorigenic and Non‐tumorigenic Cell Variants from a Rat Colon Adenocarcinoma, Induced by Dimethylhydrazine

Using NIH3T3 cell transfection assay, activated c‐K‐ras was detected in two cell lines, TRb and TSb, obtained from a single colon adenocarcinoma induced in a rat by 1,2‐dimethylhydrazine. TRb cells give rise to progressive and metastatic tumors in the syngeneic rats, whereas TSb cells only induce re...

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Detalles Bibliográficos
Autores principales:	Caignard, Anne, Kitagawa, Yoshinori, Sato, Shigeaki, Nagao, Minako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1988
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917453/ https://www.ncbi.nlm.nih.gov/pubmed/3130359 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01583.x

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