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CLONAL ORIGIN OF γ‐GLUTAMYL TRANSPEPTIDASE‐POSITIVE HEPATIC LESIONS INDUCED BY INITIATION‐PROMOTION IN ORNITHINE CARBAMOYLTRANSFERASE MOSAIC MICE

Since the deficiency of ornithine carbamoyl‐transferase (OCT) is inherited as an X‐linked dominant trait in sparse‐fur with abnormal skin and hair (Spf‐ash) mice, the livers of heterozygous Spf‐ash females show mosaicism in regard to OCT. We induced enzyme‐altered foci and nodules, presumptive prene...

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Detalles Bibliográficos
Autores principales: Tsuji, Satoru, Ogawa, Katsuhiro, Takasaka, Hajime, Sonoda, Tomoko, Mori, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917455/
https://www.ncbi.nlm.nih.gov/pubmed/2896663
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01569.x