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Inhibition of Aminoimidazoquinoxalinc‐type and Aminoimidazol‐4‐one‐type Mutagen Formation in Liquid Reflux Models by l‐Tryptophan and Other Selected Indoles

The essential amino acid l‐tryptophan (l‐Trp) was found to be an effective inhibitor of the development of mutagenicity (Ames test) in liquid‐reflux models known to produce identified IQ‐type mutagens, such as 2‐amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline (MeIQ(x)) and 2‐amino‐3,7,8‐trimethylimidazo...

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Detalles Bibliográficos
Autores principales: Jones, R. Conrad, Weisburger, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917471/
https://www.ncbi.nlm.nih.gov/pubmed/3130356
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01580.x