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Mechanism of Methotrexate‐sensitivity of Choriocarcinoma Cells in Culture
Four cell lines established from choriocarcinoma were compared for sensitivity to methotrexate (MTX). In this paper, we have compared the relative gene copy number of dihydrofolate reductase (DHFR), the target enzyme of methotrexate (MTX), in order to clarify whether or not amplification of the gene...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1988
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917478/ https://www.ncbi.nlm.nih.gov/pubmed/2836349 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01604.x |