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The Induction of Bladder Tumors in F344 Rats by Intravesicular Administration of Some Nitrosamines

Three nitrosamines, metabolically related and formed in vivo from the bladder carcinogen nitrosomethyl‐n‐octylamine, were administered to groups of 12 female F344 rats by intraurethral instillation twice a week for 30 weeks. All three compounds induced tumors in the urinary bladder. Nitrosomethyl‐2‐...

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Detalles Bibliográficos
Autores principales: Thomas, Barbara J., Kovatch, Robert M., Lijinsky, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917489/
https://www.ncbi.nlm.nih.gov/pubmed/3131281
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01592.x