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GENERATION OF INTRACELLULAR ACTIVE OXYGENS IN MOUSE FM3A CELLS BY 3‐HYDROXYAMINO‐1‐METHYL‐5H‐PYRIDO[4,3‐b]INDOLE, THE ACTIVATED TRP‐P‐2

Mouse FM3A cells in culture were treated with a reactive metabolite of 3‐amino‐1‐methyl‐5H‐pyrido[4,3‐b]indole (Trp‐P‐2), 3‐hydroxyamino‐1‐methyl ‐ 5H ‐ pyrido[4,3 ‐b]indole (Trp ‐ P ‐ 2‐ (NHOH)). When the treated cells, which were judged as viable on the basis of trypan‐blue exclusion, were subject...

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Detalles Bibliográficos
Autores principales: Wataya, Yusuke, Yamane, Kazuko, Hiramoto, Kazuyuki, Ohtsuka, Yasuharu, Okubata, Yuko, Negishi, Kazuo, Hayatsu, Hikoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917563/
https://www.ncbi.nlm.nih.gov/pubmed/2841270
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00024.x