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A SYNTHETIC SINGLE‐STRANDED DNA, POLY(dG, dC), INDUCES TNTERFERON‐α/β AND ‐γ, AUGMENTS NATURAL KILLER ACTIVITY, AND SUPPRESSES TUMOR GROWTH

When various synthetic double‐ or single‐stranded DNAs were incubated with spleen cells from mice (BALB/c or CDF(1)) at 37° for 20 hr, it was found that some of the DNAs augmented NK activity and produced factors in the culture supernatants which showed antiviral activity and activity to render mous...

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Detalles Bibliográficos
Autores principales: Tokunaga, Tohru, Yamamoto, Saburo, Namba, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917574/
https://www.ncbi.nlm.nih.gov/pubmed/2457572
http://dx.doi.org/10.1111/j.1349-7006.1988.tb02222.x