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A SYNTHETIC SINGLE‐STRANDED DNA, POLY(dG, dC), INDUCES TNTERFERON‐α/β AND ‐γ, AUGMENTS NATURAL KILLER ACTIVITY, AND SUPPRESSES TUMOR GROWTH
When various synthetic double‐ or single‐stranded DNAs were incubated with spleen cells from mice (BALB/c or CDF(1)) at 37° for 20 hr, it was found that some of the DNAs augmented NK activity and produced factors in the culture supernatants which showed antiviral activity and activity to render mous...
Autores principales: | Tokunaga, Tohru, Yamamoto, Saburo, Namba, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917574/ https://www.ncbi.nlm.nih.gov/pubmed/2457572 http://dx.doi.org/10.1111/j.1349-7006.1988.tb02222.x |
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