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Establishment and Characterization of Resistant Cells to Etoposide (VP16) from a Mouse Breast Cancer Cell Line, FM3A

We established 4 cell lines resistant to VP16 from a mouse breast cancer cell line, FM3A. The IC(50) values of all 4 resistant strains were approximately 2 μg/ml as measured by colony formation in soft agar; about 40 times higher than that of parent cell (0.05 μg/ml). These cells showed a cross‐resi...

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Detalles Bibliográficos
Autores principales: Takagi, Eishi, Kawatsu, Hidetaka, Shimokata, Kaoru, Nishiyama, Yukihiro, Kojima, Kiyohide, Yoshida, Shonen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917615/
https://www.ncbi.nlm.nih.gov/pubmed/2846485
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00058.x