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pH‐Dependent Degradation of Nitrosocimetidine and Its Mechanisms

The degradation of nitrosocimetidine (NC) and its mechanism were found to be strongly dependent upon pH by monitoring NC and its degradation products by high‐performance liquid chromatography (HPLC). NC was relatively stable at neutral pH, but it degraded rapidly under both acidic and alkaline condi...

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Detalles Bibliográficos
Autores principales: Frank, Norbert, Sato, Shigeaki, Tsuda, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917633/
https://www.ncbi.nlm.nih.gov/pubmed/3143696
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01530.x