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The Induction of Enhanced Antitumor Effect against a Nonimmunogenic Tumor by Highly Immunogenic Variants Obtained by Mutagen Treatment
Nonimmunogenic 1767‐3 fibrosarcoma was treated with the mutagen N‐methyl‐N′‐nitro‐N‐nitrosoguanidine, and stable variant cell clones (M‐clones) were obtained that were able to elicit an immunological rejection response in syngenic C3H mice. Mice immunized with some M‐clones were protected against a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917642/ https://www.ncbi.nlm.nih.gov/pubmed/3147279 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01551.x |