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Inhibitory Effect of Tamoxifen on Diethylstilbestrol‐promoted Hepatic Tumorigenesis in Male Rats and Its Possible Mechanism of Action

Male Sprague‐Dawley rats were given a single intraperitoneal injection of diethylnitrosamine (DEN, 200 mg/kg body weight). Two weeks later the rats were divided into 4 groups; DEN‐C group rats were given no further treatment; DEN‐DES group rats were fed diethylstilbestrol (DES, 0.5 mg/day); DEN‐TMX...

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Detalles Bibliográficos
Autores principales: Kohigashi, Katsuji, Fukuda, Yoshihiro, Imura, Hiroo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917654/
https://www.ncbi.nlm.nih.gov/pubmed/3148604
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01564.x