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Inhibitory Effect of Tamoxifen on Diethylstilbestrol‐promoted Hepatic Tumorigenesis in Male Rats and Its Possible Mechanism of Action
Male Sprague‐Dawley rats were given a single intraperitoneal injection of diethylnitrosamine (DEN, 200 mg/kg body weight). Two weeks later the rats were divided into 4 groups; DEN‐C group rats were given no further treatment; DEN‐DES group rats were fed diethylstilbestrol (DES, 0.5 mg/day); DEN‐TMX...
Autores principales: | Kohigashi, Katsuji, Fukuda, Yoshihiro, Imura, Hiroo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917654/ https://www.ncbi.nlm.nih.gov/pubmed/3148604 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01564.x |
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