Accumulation of Abnormally High Ploid Nuclei in the Liver of LEC Rats Developing Spontaneous Hepatitis

Enlarged hepatocytes with huge nuclei were found in LEC rats with hereditary hepatitis. Flow cytometric analysis of the DNA content of nuclei from jaundiced LEC rats revealed the presence of very high polyploids, such as 32n and 64n. At the age of 12 weeks, before the onset of hepatitis, 8n polyploi...

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Detalles Bibliográficos
Autores principales: Fujimoto, Yoshinori, Oyamada, Masahito, Hattori, Atsuo, Takahashi, Hidetoshi, Sawaki, Masakuni, Dempo, Kimimaro, Mori, Michio, Nagao, Minako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917678/
https://www.ncbi.nlm.nih.gov/pubmed/2496058
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02243.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917678/
https://www.ncbi.nlm.nih.gov/pubmed/2496058
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02243.x

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