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Effects of the Plasma Concentration of 5‐Fluorouracil and the Duration of Continuous Venous Infusion of 5‐Fluorouracil with an Inhibitor of 5‐Fluorouracil Degradation on Yoshida Sarcomas in Rats

The correlations of the 5‐fluorouracil (5‐FU) level in the plasma and the duration of continuous 5‐FU infusion with the antitumor activity of 5‐FU on Yoshida sarcomas in rats were examined. The circadian variation in the plasma level of 5‐FU during continuous infusion was prevented by treatment with...

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Detalles Bibliográficos
Autores principales: Fujii, Setsuro, Shimamoto, Yuji, Ohshimo, Hideyuki, Imaoka, Takeshi, Motoyama, Masaaki, Fukushima, Masakazu, Shirasaka, Tetsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917696/
https://www.ncbi.nlm.nih.gov/pubmed/2498251
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02285.x