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Effects of the Plasma Concentration of 5‐Fluorouracil and the Duration of Continuous Venous Infusion of 5‐Fluorouracil with an Inhibitor of 5‐Fluorouracil Degradation on Yoshida Sarcomas in Rats
The correlations of the 5‐fluorouracil (5‐FU) level in the plasma and the duration of continuous 5‐FU infusion with the antitumor activity of 5‐FU on Yoshida sarcomas in rats were examined. The circadian variation in the plasma level of 5‐FU during continuous infusion was prevented by treatment with...
Autores principales: | Fujii, Setsuro, Shimamoto, Yuji, Ohshimo, Hideyuki, Imaoka, Takeshi, Motoyama, Masaaki, Fukushima, Masakazu, Shirasaka, Tetsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1989
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917696/ https://www.ncbi.nlm.nih.gov/pubmed/2498251 http://dx.doi.org/10.1111/j.1349-7006.1989.tb02285.x |
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