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Antitumor Activity of BOF‐A2, a New 5‐Fluorouracil Derivative

A compound containing both CNDP (3‐cyano‐2,6‐dihydroxypyridine), an inhibitor of 5‐fluorouracil (5‐FU) degradation, and EM‐FU (1‐ethoxymethyl‐5‐fluorouracil), a masked form of 5‐FU, was synthesized and named BOF‐A2 (3‐[3‐(6‐benzoyloxy‐3‐cyano‐2‐pyridyloxycarbonyl)benzoyl]‐1‐ethoxymethyl‐5‐fluorourac...

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Detalles Bibliográficos
Autores principales: Fujii, Setsuro, Fukushima, Masakazu, Shimamoto, Yuji, Ohshimo, Hideyuki, Imaoka, Takeshi, Shirasaka, Tetsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917705/
https://www.ncbi.nlm.nih.gov/pubmed/2498252
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02286.x