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Efficacy of Two‐route Chemotherapy Using Intraperitoneal Neocarzinostatin and Its Antidote, Intravenous Tiopronin, for Peritoneally Disseminated Tumors in Mice

We assessed the efficacy of “two‐route chemotherapy (TRC)” using neocarzinostatin (NCS) given ip and its antidote, N‐(2‐mercaptopropionyl)‐glycine (tiopronin), given iv for peritoneally disseminated tumors in mice. Whether or not the single iv administration of tiopronin (800 mg/kg) at various times...

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Detalles Bibliográficos
Autores principales: Hasuda, Keitaro, Kobayashi, Hiroaki, Kuroiwa, Toshiro, Aoki, Ken, Taniguchi, Shun'ichiro, Baba, Tsuneo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917719/
https://www.ncbi.nlm.nih.gov/pubmed/2524462
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02306.x