Effects of Age on Multiple Organ Carcinogenesis Induced by 3,2′‐Dimethyl‐4‐aminobiphenyl in Rats, with Particular Reference to the Prostate

The effects of age on multi‐organ carcinogenesis induced by 3,2′‐dimethyl‐4‐aminobiphenyl (DMAB) in male F344 rats were examined. Groups of 5‐, 35‐, and 65‐week‐old animals were given 4 weekly sc injections of DMAB at a dose of 200 or 150 mgAg body weight. Prostate carcinomas were induced in 8 to 19...

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Detalles Bibliográficos
Autores principales: Shirai, Tomoyuki, Nakamura, Atsushi, Fukushima, Shoji, Takahashi, Satoru, Ogawa, Kumiko, Ito, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917732/
https://www.ncbi.nlm.nih.gov/pubmed/2501247
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02312.x