Differential Neutralizing Effect of Tiopronin on the Toxicity of Neocarzinostatin and SMANCS: A New Rescue Cancer Chemotherapy

The toxic effect and antitumor activity of neocarzinostatin (NCS) and SMANCS [copoly(styrenemaleic acid)‐conjugated NCS] were greatly affected by N‐(2‐mercaptopropionyl)‐glycine [tiopronm] both in vitro and in vivo, in cultured HeLa cells and RL♂1 tumor‐bearing mice. The cytotoxicity of NCS and SMAN...

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Detalles Bibliográficos
Autores principales: Oda, Tatsuya, Yamamoto, Hirotoshi, Miki, Toyohiko, Maeda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917735/
https://www.ncbi.nlm.nih.gov/pubmed/2526108
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02325.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917735/
https://www.ncbi.nlm.nih.gov/pubmed/2526108
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02325.x

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