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In vitro Targeting and Cytotoxicity of Adriamycin in Liposomes Bearing Monoclonal Antibody against Rat or Human gp125 Cell Proliferation‐associated Antigen

Chemoimmunoliposomes (CIL) were prepared by entrapping adriamycin in monoclonal antibody (mAb)‐coated liposomes and examined for their binding capacity and cytotoxicity to relevant target tumor cells. Sonicated unilamellar liposomes were coated with B3 and HBJ127 mouse, mAbs, which recognize a rat a...

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Detalles Bibliográficos
Autores principales: Tanaka, Toshiyuki, Suzuki, Shinya, Masuko, Takashi, Hashimoto, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917737/
https://www.ncbi.nlm.nih.gov/pubmed/2501255
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02323.x