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Altered Expression of Epidermal Growth Factor Receptor Gene in a Classical Multidrug‐resistant Variant of a Human Cancer Cell Line, KB

A variant clone resistant to high doses of colchicine (KB‐C1) derived from human cancer KB cell line is resistant to various anticancer agents. The KB‐C1 cells were much more resistant to epidermal growth factor and a chimeric toxin, EGF‐Pseudomottas exotoxin (PE), than the parental KB cells. KB‐C1...

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Detalles Bibliográficos
Autores principales: Takano, Hiroshi, Kohno, Kimitoshi, Shiraishi, Norio, Sato, Shin‐ichi, Asoh, Kuni‐ichi, Yakushinji, Miki, Ono, Mayumi, Kuwano, Michihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917741/
https://www.ncbi.nlm.nih.gov/pubmed/2501254
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02322.x