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Distinct effects of apathy and dopamine on effort-based decision-making in Parkinson’s disease

Effort-based decision-making is a cognitive process crucial to normal motivated behaviour. Apathy is a common and disabling complication of Parkinson’s disease, but its aetiology remains unclear. Intriguingly, the neural substrates associated with apathy also subserve effort-based decision-making in...

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Detalles Bibliográficos
Autores principales: Le Heron, Campbell, Plant, Olivia, Manohar, Sanjay, Ang, Yuen-Siang, Jackson, Matthew, Lennox, Graham, Hu, Michele T, Husain, Masud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917786/
https://www.ncbi.nlm.nih.gov/pubmed/29672668
http://dx.doi.org/10.1093/brain/awy110