Antitumor Activity and Pharmacology of 1‐β‐D‐Arabinofuranosylcytosine‐5′‐stearylphosphate: An Orally Active Derivative of 1‐β‐D‐Arabinofuranosylcytosine

The antitumor activity of l‐β‐D‐arabinofuranosylcytosine‐5′‐alkylphosphates (CnPCAs) against L1210 leukemia in mice after oral administration was demonstrated. The optimum length of the alkyl group on the phosphate moiety of CnPCA for exhibiting a high antitumor activity was found to be between tetr...

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Detalles Bibliográficos
Autores principales: Kodama, Kenjiro, Morozumi, Manami, Saitoh, Ken‐ichi, Kuninaka, Akira, Yoshino, Hiroshi, Saneyoshi, Mineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917809/
https://www.ncbi.nlm.nih.gov/pubmed/2507491
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01696.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917809/
https://www.ncbi.nlm.nih.gov/pubmed/2507491
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01696.x

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