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Antitumor Activity and Pharmacology of 1‐β‐D‐Arabinofuranosylcytosine‐5′‐stearylphosphate: An Orally Active Derivative of 1‐β‐D‐Arabinofuranosylcytosine
The antitumor activity of l‐β‐D‐arabinofuranosylcytosine‐5′‐alkylphosphates (CnPCAs) against L1210 leukemia in mice after oral administration was demonstrated. The optimum length of the alkyl group on the phosphate moiety of CnPCA for exhibiting a high antitumor activity was found to be between tetr...
Autores principales: | Kodama, Kenjiro, Morozumi, Manami, Saitoh, Ken‐ichi, Kuninaka, Akira, Yoshino, Hiroshi, Saneyoshi, Mineo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1989
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917809/ https://www.ncbi.nlm.nih.gov/pubmed/2507491 http://dx.doi.org/10.1111/j.1349-7006.1989.tb01696.x |
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