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Inhibitory Effect of Chitin Heparinoids on the Lung Metastasis of B16‐BL6 Melanoma

Structure‐function studies for the antimetastatic activity of chemically modified chitin heparinoids composed of N‐acetyl glucosamine units were performed in an experimental lung metastasis model. 6‐O‐Sulfatcd chitin (S‐chitin) significantly inhibited the lung tumor colonization in proportion to the...

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Detalles Bibliográficos
Autores principales: Murata, Jun, Saiki, Ikuo, Nishimura, Shin‐ichiro, Nishi, Norio, Tokura, Seiichi, Azuma, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917858/
https://www.ncbi.nlm.nih.gov/pubmed/2513303
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01728.x