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Inhibition of Tumor Cell Invasion by Ubenimex (Bestatin) in vitro

We have investigated the effect of the immunomodulator ubenimex (bestatin) on tumor cell invasion of reconstituted basement membrane (Matrigel). The invasion of B16‐BL6 melanoma cells and Lewis lung carcinoma (3LL) cells into Matrigel‐coated filters was inhibited by the presence of bestatin in a con...

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Detalles Bibliográficos
Autores principales: Saiki, Ikuo, Murata, Jun, Watanabe, Kunihito, Fujii, Hideji, Abe, Fuminori, Azuma, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917861/
https://www.ncbi.nlm.nih.gov/pubmed/2513304
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01729.x