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Change in Methylation Status of DNA of Remaining Allele in Human Lung Cancers with Loss of Heterozygosity on Chromosomes 3p and 13q

Loss of heterozygosity at several chromosomal loci is frequently observed in human cancers and loss of one allele is supposed to affect expression of the gene(s) in the remaining allele. As DNA methylation is known to be closely related to gene expression in vertebrates, we are interested in the met...

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Detalles Bibliográficos
Autores principales: Shiraishi, Masahiko, Sekiya, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917876/
https://www.ncbi.nlm.nih.gov/pubmed/2482283
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01627.x