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A New, Potent 2‐Nitroimidazole Nucleoside Hypoxic Cell Radiosensitizer, RP170

The radiosensitizing activity, acute toxicity and pharmacokinetics of RP170, a new hypoxic cell radiosensitizer, were compared with those of misonidazole (MISO) and SR2S08. RP170 belongs to the group of 2‐nitroimidazole nucleosides, which are designed to be selectively excluded from the neural tissu...

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Detalles Bibliográficos
Autores principales: Sasai, Keisuke, Shibamoto, Yuta, Takahashi, Masaji, Abe, Mitsuyuki, Wang, Jun, Zhou, Lin, Nishimoto, Sei‐ichi, Kagiya, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917901/
https://www.ncbi.nlm.nih.gov/pubmed/2532634
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02267.x