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A Novel Multidrug Resistance in Cultured Leukemia and Lymphoma Cells Detected by a Monoclonal Antibody to 85‐kDa Protein, MRK20

A monoclonal antibody, MRK20, in F(ab′)(2) form [MRK20‐F(ab′)(2)], which reacts with 85‐kDa membrane protein in a doxorubicin (ADM)‐resistant subline (K562/ADM) of human myelogenous leukemia cell line, K562, was examined for reactivity with 41 cultured human leukemia and lymphoma cell lines. None of...

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Detalles Bibliográficos
Autores principales: Ohtsu, Tomoko, Ishida, Yasushi, Tobinai, Kensei, Minato, Keisuke, Hamada, Hirofumi, Ohkochi, Etsuko, Tsuruo, Takashi, Shimoyama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917903/
https://www.ncbi.nlm.nih.gov/pubmed/2514173
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02270.x