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Association of Elevated Expression of the c‐erbB‐2 Protein with Spread of Breast Cancer
We analyzed amplification and expression of the c‐erbB‐2 gene in human breast cancers. Southern blot hybridization analysis demonstrated amplification of the c‐erbB‐2 gene in 10 out of 50 tumor DNAs examined. The degree of amplification was three‐ to twenty‐fold relative to normal placenta. The c‐er...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1989
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917922/ https://www.ncbi.nlm.nih.gov/pubmed/2576425 http://dx.doi.org/10.1111/j.1349-7006.1989.tb01654.x |