DNA Modification by 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine in Rats

2‐Amino‐l‐methyl‐6‐pheny]imidazo[4,5‐b]pyridine (PhIP) is the most abundant mutagenic heterocyclic amine by weight in cooked foods. This mutagen was found to produce DNA adducts in all ten tested organs of rats using the (32)P‐postlabeling method. The level of DNA adducts in the pancreas, kidney and...

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Detalles Bibliográficos
Autores principales: Takayama, Kyoko, Yamashita, Katsumi, Wakabayashi, Keiji, Sugimura, Takashi, Nagao, Minako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917929/
https://www.ncbi.nlm.nih.gov/pubmed/2516840
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01644.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917929/
https://www.ncbi.nlm.nih.gov/pubmed/2516840
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01644.x

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