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DNA Modification by 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine in Rats
2‐Amino‐l‐methyl‐6‐pheny]imidazo[4,5‐b]pyridine (PhIP) is the most abundant mutagenic heterocyclic amine by weight in cooked foods. This mutagen was found to produce DNA adducts in all ten tested organs of rats using the (32)P‐postlabeling method. The level of DNA adducts in the pancreas, kidney and...
Autores principales: | Takayama, Kyoko, Yamashita, Katsumi, Wakabayashi, Keiji, Sugimura, Takashi, Nagao, Minako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1989
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917929/ https://www.ncbi.nlm.nih.gov/pubmed/2516840 http://dx.doi.org/10.1111/j.1349-7006.1989.tb01644.x |
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