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Monoclonal Anti‐P‐glycoprotein Antibody‐dependent Killing of Multidrug‐resistant Tumor Cells by Human Mononuclear Cells

Mouse monoclonal antibodies (MRK16 and MRK17) against human multidrug‐resistant cancer cell lines were tested for antibody‐dependent cytotoxicity mediated by human blood mononuclear cells, using a 4‐h (51)Cr release assay. MRK16 (IgG(28) isotype) was shown to be more effective than MRK17 (IgG(1) iso...

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Detalles Bibliográficos
Autores principales: Heike, Yuji, Hamada, Hirofumi, Inamura, Noriaki, Sone, Saburo, Ogura, Takeshi, Tsuruo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917982/
https://www.ncbi.nlm.nih.gov/pubmed/1979977
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02528.x