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High Yields of Granulosa Cell Tumors/Luteomas in F344 Rat Ovaries after Transplacental Administration of N‐Nitrosobis(2‐oxopropyl)amine

Ovarian tumors were induced at very high incidence in the offspring of F344 rats receiving 3 subcutaneous injections of 10 mg/kg of N‐nitrosobis(2‐oxopropyl)amine on the 14th, 18th and 20th days of gestation. Histologically, all ovarian tumors were of the granulosa cell tumor and/or luteoma type. Ma...

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Detalles Bibliográficos
Autores principales: Maekawa, Akihiko, Onodera, Hiroshi, Matsushima, Yuko, Nagaoka, Takaharu, Todate, Asahi, Kanno, Jun, Shibutani, Makoto, Ogasawara, Hiroyuki, Yoshida, Junichi, Hayashi, Yuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917986/
https://www.ncbi.nlm.nih.gov/pubmed/2176198
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02514.x