Inhibition of abl Oncogene Tyrosine Kinase Induces Erythroid Differentiation of Human Myelogenous Leukemia K562 Cells

The human chronic myelogenous leukemia cell line K562 expresses a structurally altered c‐abl protein with tyrosine kinase activity. Erythroid differentiation of K562 cells was induced by tyrosine kinase inhibitors, but not by other kinase inhibitors. Treatment of K562 cells with 5'd(TACTGGCCGCT...

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Detalles Bibliográficos
Autores principales: Honma, Yoshio, Okabe‐Kado, Junko, Kasukabe, Takashi, Hozumi, Motoo, Umezawa, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917994/
https://www.ncbi.nlm.nih.gov/pubmed/2125038
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02524.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917994/
https://www.ncbi.nlm.nih.gov/pubmed/2125038
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02524.x

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