Optimal Treatment Regimens for 5′‐Deoxy‐5‐fluorouridine, with or without (E)‐5‐(2‐Bromovinyl)‐2′‐deoxyuridine, against Various Tumors in Mice

The antitumor activity of 5′‐deoxy‐5‐fluorouridine (DFUR), a prodrug of 5‐fluorouracil (5‐FU), is markedly enhanced if DFUR treatment is combined with (E)‐5‐(2‐bromovinyl)‐2′‐deoxyuridine (BVDU). Combined oral administration of DFUR (10 mg/kg) and BVDU (10 mg/kg) three times (every 3 h) per day for...

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Detalles Bibliográficos
Autores principales: Iigo, Masaaki, Miwa, Masanori, De Clercq, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918056/
https://www.ncbi.nlm.nih.gov/pubmed/2142152
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02586.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918056/
https://www.ncbi.nlm.nih.gov/pubmed/2142152
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02586.x

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