Mutational Activation of H‐ras and K‐ras Genes Is Absent in N‐Nitroso‐N‐methylurea‐induced Liver Tumors in Rats

We examined mutational activation of H‐ and K‐ras genes in hyperplastic nodules and hepatocellular carcinomas induced by N‐nitroso‐N‐methylurea or diethylnitrosamine using the polymerase chain reaction, followed by dot‐blot hybridization. No mutational activation was detected in these hepatic lesion...

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Detalles Bibliográficos
Autores principales: Sakai, Hirotsuka, Ogawa, Katsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918065/
https://www.ncbi.nlm.nih.gov/pubmed/2116389
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02587.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918065/
https://www.ncbi.nlm.nih.gov/pubmed/2116389
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02587.x

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