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Determinants of Drug Response in a Cisplatin‐resistant Human Lung Cancer Cell Line

To elucidate the mechanism(s) of cisplatin resistance, we have characterized a human non‐small cell lung cancer cell line (PC‐9/CDDP) selected from the wild type (PC‐9) for acquired resistance to cisplatin. PC‐9/CDDP demonstrated 28‐fold resistance to cisplatin, with cross resistance to other chemot...

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Detalles Bibliográficos
Autores principales: Fujiwara, Yasuhiro, Sugimoto, Yoshikazu, Kasahara, Kazuo, Bungo, Masami, Yamakido, Michio, Tew, Kenneth D., Saijo, Nagahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918066/
https://www.ncbi.nlm.nih.gov/pubmed/2116401
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02602.x