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Antitumor Activity and Pharmacokinetics of a Morpholino‐anthracycline Derivative (KRN8602) against Human Breast Carcinoma Xenografts Serially Transplanted into Nude Mice

The antitumor activity and pharmacokinetics of (7R, 8S, 10S)‐10‐((3‐deamino‐3‐(4‐morpholino)‐2,3,6‐trideoxy‐α‐l‐lyxo‐hexopyranosyl)oxy)‐8‐ethyl‐7,8,9,10‐tetrahydro‐1,6,7,8,11‐pentahydroxy‐5,12‐naphthacenedione hydrochloride (KRN8602) were evaluated using five human breast carcinoma xenografts in nud...

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Detalles Bibliográficos
Autores principales: Kubota, Tetsuro, Suto, Akihiko, Josui, Kazuya, Ishibiki, Kyuya, Abe, Osahiko, Yamada, Yoshinori, Asanuma, Fumiki, Kawamura, Eiji, Koh, Jun‐ichi, Shiina, Eiichi, Inada, Takao, Ogata, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918099/
https://www.ncbi.nlm.nih.gov/pubmed/2144515
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02652.x