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Overexpression of 11β-hydroxysteroid dehydrogenase 1 in visceral adipose tissue and underexpression of endothelial nitric oxide synthase in the adrenal cortex of dogs with hyperadrenocorticism

11β-Hydroxysteroid dehydrogenase 1 (11β-HSD1) is an enzyme that activates cortisone into cortisol in tissues. Alterations in this enzyme are related to the development of metabolic syndrome, obesity and hyperadrenocorticism (HAC). Endothelial nitric oxide synthase (eNOS) produces nitric oxide and is...

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Detalles Bibliográficos
Autores principales: Miceli, Diego Daniel, Abiuso, Adriana María Belén, Vidal, Patricia Noemi, Gallelli, María Florencia, Pignataro, Omar Pedro, Castillo, Victor Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of Veterinary Medicine, University of Tripoli and Libyan Authority for Research, Science and Technology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918128/
https://www.ncbi.nlm.nih.gov/pubmed/29721436
http://dx.doi.org/10.4314/ovj.v8i1.13