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Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner
Antibiotics are widely used to treat infections in humans. However, the impact of antibiotic use on host cells is understudied. Here we identify an antiviral effect of commonly used aminoglycoside antibiotics. We show that topical mucosal application of aminoglycosides prophylactically increased hos...
Autores principales: | Gopinath, Smita, Kim, Myoungjoo V., Rakib, Tasfia, Wong, Patrick W., van Zandt, Michael, Barry, Natasha A., Kaisho, Tsuneyasu, Goodman, Andrew L., Iwasaki, Akiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918160/ https://www.ncbi.nlm.nih.gov/pubmed/29632368 http://dx.doi.org/10.1038/s41564-018-0138-2 |
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