A Non-apoptotic Function of MCL-1 in Promoting Pluripotency and Modulating Mitochondrial Dynamics in Stem Cells

Human pluripotent stem cells (hPSCs) maintain a highly fragmented mitochondrial network, but the mechanisms regulating this phenotype remain unknown. Here, we describe a non-cell death function of the anti-apoptotic protein, MCL-1, in regulating mitochondrial dynamics and promoting pluripotency of s...

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Detalles Bibliográficos
Autores principales: Rasmussen, Megan L., Kline, Leigh A., Park, Kyungho P., Ortolano, Natalya A., Romero-Morales, Alejandra I., Anthony, Christin C., Beckermann, Kathryn E., Gama, Vivian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918190/
https://www.ncbi.nlm.nih.gov/pubmed/29429957
http://dx.doi.org/10.1016/j.stemcr.2018.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918190/
https://www.ncbi.nlm.nih.gov/pubmed/29429957
http://dx.doi.org/10.1016/j.stemcr.2018.01.005

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