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Neurons Generated by Mouse ESCs with Hippocampal or Cortical Identity Display Distinct Projection Patterns When Co-transplanted in the Adult Brain

The capability of generating neural precursor cells with distinct types of regional identity in vitro has recently opened new opportunities for cell replacement in animal models of neurodegenerative diseases. By manipulating Wnt and BMP signaling, we steered the differentiation of mouse embryonic st...

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Detalles Bibliográficos
Autores principales: Terrigno, Marco, Busti, Irene, Alia, Claudia, Pietrasanta, Marta, Arisi, Ivan, D'Onofrio, Mara, Caleo, Matteo, Cremisi, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918192/
https://www.ncbi.nlm.nih.gov/pubmed/29456186
http://dx.doi.org/10.1016/j.stemcr.2018.01.010