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Loss of Heterozygosity on Chromosome 1p in Thyroid Adenoma and Medullary Carcinoma, but not in Papillary Carcinoma

We analyzed 53 loci on 21 chromosomes other than chromosome 4 to detect possible loss of heterozygosity in 31 thyroid tumors using polymorphic DNA markers that detect allelic deletions at specific chromosomal loci. Loss of heterozygosity on chromosomes 1, 7 and 12 was detected in one follicular thyr...

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Detalles Bibliográficos
Autores principales: Kubo, Katsuyuki, Yoshimoto, Katsuhiko, Yokogoshi, Yutaka, Tsuyuguchi, Masaru, Shiro, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918246/
https://www.ncbi.nlm.nih.gov/pubmed/1683348
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01763.x